Mousepad keyboard shortcuts (accelerators) and XFCE HID standard adherence
Mousepad uses Ctrl-R as a keyboard shortcut (aka accelerator) for Search and Replace. According to https://wiki.xfce.org/dev/hig/general "Generally Xfce uses the guidelines found in GNOME Human Interface Guidelines 2.0." (the link being dead, by the way) The Gnome 2 HIG (if you want to stick to that version, although it is apparently considered outdated by Gnome) can be found here: https://developer-old.gnome.org/hig-book/ On https://developer-old.gnome.org/hig-book/3.12/menus-standard.html it stipulates that the shortcut for Search and Replace should be Ctrl-H. So do the current gnome HIG (found at https://developer.gnome.org/hig/) say, specifically at https://developer.gnome.org/hig/reference/keyboard.html "Replace Ctrl+H Shows and focuses a find and replace UI." In contrast it specifies "Reload Ctrl+R Reloads the current view or content item." For improved HI design consistency I therefore suggest sticking to that standard.